Descriptor Spanish: Absceso Hepático Amebiano. Descriptor Portuguese: Abscesso Hepático Amebiano. Synonyms English: Amoebiasis, Hepatic Hepatic . specific purulent invasive lesion commonly of the liver caused by parasiticamebas abscesso amebiano um conjunto depus no fígado causada porum parasita. Como esperado, o tratamento com dexametasona no modelo murino de abscesso hepático amebiano reduziu o infiltrado inflamatório, no entanto.

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The content of its central cavity is a thick, clotty exudate. Because ambiano its highly lethal action against the trophozoite of Entamoeba histolytica and favorable pharmacokinetics, with fast intestinal absorption, excellent bioavailability, widespread distribution in most body tissues and a half-life of 14 hours, metronidazole is the indicated drug for the treatment of hepatic amebiasis [47].

Nowadays, the prognosis of hepatic amebiasis, diagnosed early and properly treated, is quite favorable and mortality should be approximately zero. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

Hepatic amebiasis

The binding of antibodies to trophozoites was significantly higher in hamsters inoculated with E. Reported in the metropolitan regions of developing countries, hepatic amebiasis is endemic in Thailand, India, Egypt and South Africa, with high mortality rates [1]. Laparoscopic drainage of liver abscess.

The trophozoites invade the submucosa and spread out laterally, creating the classic flask-shaped amebic ulcer [13] Figure 1. J Trop Med Hyg ; It often involves the right chest, although the left side can abscesxo be affected.


Hepatic cavity healing may occur within from 3 to 12 months and must be monitored by ultrasonography. In the majority of cases, a mild to moderate leukocytosis is present, with an average white blood cell count of 16, Diagnosis After the old days of splenoportography and less sensitive tests, the non-invasive imaging procedures, including abscessi, computerized tomography, magnetic resonance imaging and, principally serology, have dramatically improved the clinician’s ability to promptly diagnosis hepatic amebiasis and aebiano start treatment.

In chronic forms the fever is low and develops more gradually, without chills or sweating. Pneumopericardium complicating amoebic liver abscess.

Surg Gynecol Obstet ;; Although necrosis has proven lower in mice in the groups treated with dexamethasone, this difference was not statiscally significant. Tumors of the liver and intrahepatic bile ducts.

amebíase / Entamoeba histolytica

Membrane-bound acid phosphatase MAP from Entamoeba histolytica has phosphotyrosine phosphatase activity and disrupts the actin cytoskeleton of host cells. The extension of the hepatic amebiasis to the pericardium, also aebiano a mechanism of contiguity, is responsible for serious syndromes that range from mild pericarditis to catastrophic purulent pericarditis [38,39,40].

J Comput Assist Tomogr ; Services on Demand Journal. A comparison of amebic and pyogenic abscesses of the liver.

BMJ Best Practice

Pathogenesis of intestinal amoebiasis: Ruptured amebic liver abscess. Amebic liver abscess and its complications. Journal of Hepatology, v.

Clin Infect Dis ; Nitazoxanida for the treatment of intestinal protozoan and helminthic infections. In the larger abscesses, a mass or a lump may sometimes be seen in the right hypochondria or epigastria [15] Figure 4. Hepatogastrenterology ; Though there is insufficient data on human beings, the mutagenic and carcinogenic potential of metronidazole has been widely studied in animals [48].


Following amebiabo of the protective mucus blanket, trophozoites attach to the cells of interglandular epithelium and, with the aid of proteolytic enzymes that degrade elastin, collagen and fibronectin, especially cysteine proteinase, phospholipase and hemolysin [12], they invade amebuano colonic epithelium by disruption of the extra cellular matrix.

It can then establish persistent extra-intestinal infection throughout the portal veins radicles, most amebiamo in the liver [10].

Amebic peritonitis following ruptures of an amebic liver abscess. Tumor calcification following therapy. A retrospective study of 1, consecutive CT scans of the abdomen was carried out to determine the presence of intrahepatic calcifications.

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Outcome on untreated infection with Wbscesso histolytica in homosexual men with and without HIV antibody. In both groups non-treated with dexamethasone, the immune- histochemistry analysis demonstrated the prevalence of macrophages in the inflammatory infiltrate both amebianl the border areas of necrosis and in the inflammatory foci.

Differential Diagnosis Despite a similarity with several diseases such as hepatoma, acute cholecystitis, parasitic cysts, subphrenic and pulmonary abscesses provoked by bacteria, the differential diagnosis of hepatic amebiasis must be established principally against pyogenic abscess [30,31].

Two of these patients presented calcifications only after chemotherapy. Intrahepatic calcifications were found in 3.