The tree is harvested from the wild for local use as a medicine, food, and as a source of oil and wood. Known Hazards. The bark is used as a fish poison[. () Medicinal Importance of Holoptelea Integrifolia (Roxb).Planch – Its Biological and Pharmacological Activities. Nat Prod Chem Res doi. Common name: Indian Elm, entire-leaved elm tree, jungle cork tree, south Indian elm tree • Hindi: चिलबिल chilbil, कान्जू kanju, पपड़ी.

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Occurrence Occurrence Occurrence Records. Besides, the external application of these extracts on the wound prevented the microbes from invading the holoptelra, resulting in the protection of wound against the microbial infections. The plant species contains wide range of phytochemicals such as terpenoids, sterols, saponins, tannins, proteins, carbohydrates, and alkaloids [ 1852 ].

BioMed Research International

The ripe fruits, known as samaras. The diethyl ether extract has shown the highest activity and the active principle responsible for the present activity was found to be 1, 4-naphthalenedione. View at Google Scholar M. Many compounds were isolated from the plant and proven to be biologically active. Hypolipidemic or antihyperlipidemic agents are lipid-lowering drugs that are used in the treatment of hyperlipidemias. Herbal medicines have recently attracted much attention as alternative medicines useful for treating or preventing lifestyle-related disorders, but relatively very little knowledge is available about their mode of action.


Chemical tests have been employed in the preliminary phytochemical screening for alcoholic extract of Holoptelea integrifolia. Ann Agric Environ Med Branches heavily laden with the developing fruits Photograph by: Bishen singh and Mahendrapal singh publisher,dehradun, India, Cisplatin-induced pica decreased significantly when animals were pretreated with H. The family Ulmaceae is comprised of species belonging to 15 genera which are distributed in tropical temperate regions of Northern Hemisphere.

Holoptelea integrifolia

Herbal remedies of Nainital district, U. These phytocompounds may cause inhibition of ATP-sensitive potassium channels in pancreatic beta cells.

Among all the extracts tested, methanolic and aqueous extracts showed better and dose-dependent activity in comparison with reference standard piperazine citrate. A vast proportion of the available higher plant species have not yet been screened for biologically active compounds; drug discovery from plants should remain an essential component in the search for new medicines.

Similarly, ethyl acetate extract was selectively approx. However, the first study towards the analgesic activity of Holoptelea integrifolia was observed by Rizwani et al. This is an open access paper distributed under the copyright agreement with Serials Publication, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited Related article at PubmedScholar Google.

View at Google Scholar J. Renu, Sanjana Julias Thilakar, D. Flowers polygamous, appear before leaves, mm across, greenish-purple, in axillary fascicles; tepals 4 or holkptelea, free, anthers pubescent; female flowers with longer pedicels; ovary superior, compressed, long stipitate, 2-winged, 1-celled, ovule 1; style 2 fid.

In male flowers, there are 8 stamens and in bisexual flowers 5 stamens are present. Various secondary metabolites such as tannins, cardiac glycosides, alkaloids, saponins, anthracene derivatives and cyanogenic glycoside have been detected by chemical test [ 20 – 22 ].


India Biodiversity Portal

These extracts showed significant anti-diabetic activity [ 32 ]. Found in deciduous forests and river banks from foothills to m. Ashoka Trust for Research in Ecology and the Environment, The results were comparable with reference standard glibenclamide. Bulk of pollens originates from anemophilous trees and grasses.

Hence, an attempt was made to update the complete information on botany, phytochemistry, and pharmacological holopttelea of the species. Decoction of the bark is applied to cure rheumatism.

There are about 47, plant species in India, out of which 7, plant species are of medicinal value; only plant species are used in the preparation of herbal drugs. The ethanolic leaf extract of H.

Chemistry and medicinal properties of Holoptelea integrifolia. The mucilaginous bark is boiled and the juice squeezed out and applied to rheumatic swellings [ 7 ]. The yield value of both the leaves extract is recorded. Agrobios Publication, Jodhpur, India, integrlfolia Presence of a compound 3- 7-ethoxymethyloxo-2H-chromenyl propanoate C1 in the test extract could be responsible for the present activity,which might have inhibited HMGR activity and block intestinal fat absorption.